Myeloablative chemotherapy with autologous bone marrow rescue in young children with recurrent malignant brain tumors. J Clin Oncol ; 16 : — Intensive chemotherapy and bone marrow rescue for young children with newly diagnosed malignant brain tumors. Is there a role for myeloablative chemotherapy with autologous hematopoietic cell rescue in the management of childhood high-grade astrocytomas? Pediatr Blood Cancer ; 54 : — Outcome for young children newly diagnosed with ependymoma, treated with intensive induction chemotherapy followed by myeloablative chemotherapy and autologous stem cell rescue.
Materials and Methods
Pediatr Blood Cancer ; 49 : 34— Finlay JL, Zacharoulis S. The treatment of high grade gliomas and diffuse intrinsic pontine tumors of childhood and adolescence: a historical—and futuristic—perspective.
- Pediatric Cancer, Volume 2 [electronic resource] : Teratoid / Rhabdoid, Brain Tumors, and Glioma.
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J Neurooncol ; 75 : — Toxicity of tandem high-dose chemotherapy and autologous stem cell transplantation using carboplatin-thiotepa-etoposide and cyclophosphamide-melphalan regimens for malignant brain tumors in children and young adults. J Neurooncol ; : — Tandem high-dose chemotherapy and auto-SCT for malignant brain tumors in children under 3 years of age.
Bone Marrow Transplant ; 48 : — Improving survival in recurrent medulloblastoma: earlier detection, better treatment or still an impasse? Br J Cancer ; 77 : — Pediatr Blood Cancer ; 51 : — High-dose chemotherapy with autologous stem cell rescue for children with recurrent malignant brain tumors. Phase I study of tandem high-dose chemotherapy with autologous peripheral blood stem cell rescue for children with recurrent brain tumors: a Pediatric Blood and Marrow Transplant Consortium study.
Pediatr Blood Cancer ; 57 : — High-dose chemotherapy with autologous stem-cell rescue in patients with recurrent and high-risk pediatric brain tumors. J Clin Oncol ; 15 : — Pilot study of high-dose thiotepa and etoposide with autologous bone marrow rescue in children and young adults with recurrent CNS tumors.
Pediatric Cancer, Volume 2: Teratoid/Rhabdoid, Brain Tumors, and Glioma
The Children's Cancer Group. J Clin Oncol ; 14 : — High-dose carboplatin, thiotepa, and etoposide with autologous stem cell rescue for patients with previously irradiated recurrent medulloblastoma. Neuro Oncol ; 12 : — Efficacy of high-dose chemotherapy or standard salvage therapy in patients with recurrent medulloblastoma.
Neuro Oncol ; 10 : — Gajjar A, Pizer B. Role of high-dose chemotherapy for recurrent medulloblastoma and other CNS primitive neuroectodermal tumors. High-dose chemotherapy with autologous stem-cell rescue in the treatment of patients with recurrent non-cerebellar primitive neuroectodermal tumors. Pediatr Blood Cancer ; 42 : — Download references. Correspondence to J A Guerra. Reprints and Permissions. Guerra, J. Marrow-ablative chemotherapy followed by tandem autologous hematopoietic cell transplantation in pediatric patients with malignant brain tumors.
Bone Marrow Transplant 52, — doi Download citation. JAMA Advanced search. Skip to main content. Subjects Chemotherapy Haematopoietic stem cells. Abstract To improve survival in young children with malignant brain tumors, irradiation-avoiding or -minimizing marrow-ablative chemotherapy HDCx with autologous hematopoietic cell transplantation AuHCT has been investigated. Access through your institution.
Peripheral biomarkers for pediatric brain tumors: current advancements and future challenges
Buy or subscribe. Download PDF. Introduction Central nervous system CNS tumors are the second most common pediatric malignancies after acute leukemias and are the most common pediatric solid tumors. This article summarizes data from collaborative group and institutional trials that have advanced the science of pediatric brain tumors and survival of patients with these tumors.
Advanced genomic analysis of the entire spectrum of pediatric brain tumors has heralded an era in which stakeholders in the pediatric neuro-oncology community are being challenged to reconsider their current research and diagnostic and treatment strategies.
go The incorporation of this new information into the next-generation treatment protocols will unleash new challenges. The potential impact of this new information on future clinical protocols also is discussed.
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Cutting-edge genomics technologies and the information gained from such studies are facilitating the identification of molecularly defined subgroups within patients with particular pediatric brain tumors. Original Article Free Access.
Patients and clinicopathological data
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